Kite Pharma Defies Skeptics and Rewards Bulls With a Big Buyout

Bears who went into the weekend incredulous that shares of Kite Pharma Inc. had soared 200 percent in 2017 awoke Monday to learn the gain is now 300 percent.

One of the medical industry’s biggest battlefield stocks is resolving resoundingly in favor of the bulls with news that Kite agreed to be bought by Gilead Sciences Inc. for $11.9 billion, or $180 a share. The price represents a 29 percent premium over the last closing price for a stock whose precipitous climb had drawn caution from analysts long before Monday’s news.

Among biotechs, a group not exactly known for restrained valuations, Kite was already trading higher than any other stock relative to analyst price forecasts — $27 higher — as of Friday. Its new blood cancer therapy, axi-cel, faces a litany of questions about competition, the complexity of its manufacturing process and how it will be paid for by insurers.

Real as those concerns may have been, they are no longer a problem for anyone holding the shares. Kite jumped to $179.05 in pre-market trading, a price that represents the addition of almost $9.7 billion in market value for the erstwhile small cap since the start of the year. At the proposed takeover price Kite would be bigger than 130 constituents of the S&P 500.

Axi-cel is awaiting a U.S. regulatory decision in non-Hodgkin lymphoma by Nov. 29. The issue has never been approval — that’s expected, and the market could be billions. Less clear was whether Kite could capitalize on the treatment fast enough to justify a stock that traded for 39 times estimated 2018 sales.

And bearish bets on Kite were substantial. As of mid-August, short interest amounted to about eight days worth of Kite’s average trading volume, a days-to-cover ratio in the upper third of 2,500 Nasdaq-traded companies, according to exchange data compiled by Bloomberg.

Axi-cel is part of a new class of cancer treatments known as chimeric antigen receptor T-cell (CAR-T) therapies, which work by extracting immune cells, re-engineering them to attack a tumor, and then infusing them back into the body. Estimating the cost of care is challenging because patients can only be treated in a limited number of medical centers and must be monitored for potentially deadly side effects.

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